Important Safety Information: Certain patients should not use CERDELGA based on their CYP2D6 metabolizer status due to an increased risk of side effects, including heart problems. Do not use CERDELGA if you are an Extensive Metabolizer (EM) taking a medicine that is a strong or moderate CYP2D6 inhibitor along with another medicine that is a strong or... View more

Treatment Options

Treatment options are available to help manage the signs and symptoms of Gaucher disease, including oral therapy. The goal of treatment is to reduce or prevent the build-up of GL-1.

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patient with Gaucher disease type 1 treated with Cerdelga

Treatment options for Gaucher disease type 1

While there is no cure, if you have been diagnosed with Gaucher disease type 1, treatment approaches are available to manage the disease, including oral medicine. The goal of these treatments is to reduce or prevent the buildup of GL-1. Treatment outcomes may vary among patients.

2 treatment approaches for Gaucher disease type 1:
Substrate reduction therapy (SRT)

SUBSTRATE REDUCTION THERAPY (SRT)

  • Oral medicine taken daily
  • Reduces the amount of GL-1 that is produced
Enzyme Replacement Therapy (ERT)

ENZYME REPLACEMENT THERAPY (ERT)

  • Intravenous (IV) infusions usually given every 2 weeks at an infusion center, a doctor’s office, or at home as medically appropriate (Infusion takes approximately 1-2 hours)
  • Adds a modified version of the enzyme to help your body break down GL-1

Most adult patients newly diagnosed with Gaucher disease type 1 can begin treatment with an oral therapy, and it is possible for most adult patients with Gaucher disease type 1 currently being treated with an ERT (infusion) to switch to an oral therapy. Your doctor will know the best course of treatment for you.

Cerdelga® (eliglustat) is the ONLY first-line oral SRT. Talk to your doctor about your treatment options